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Dr.
Mechthild Tegeder
.jpg) 509-335-7545
tegeder@wsu.edu
Associate
Professor of Biological Sciences, Center for Reproductive Biology,
Center for Integrated Biotechnology. Ph.D. Free University of
Berlin and University of Goettingen.
Research
Nitrogen
is often a limiting factor to plant growth and development. Its
distribution within the plant, mainly in the form of amino acids,
is particularly important to generation of vegetative (tubers,
bulbs, storage roots, etc.) and reproductive (flowers, seeds)
organs. We are studying the transport of amino acids and
other organic compounds, like ureides, from roots and leaves
where they are produced to sink organs (like seeds) where they
are essential for development and accumulation of storage compounds.
Several classes of putative organic nitrogen transporters have
been identified in plants. Using molecular, biochemical,
cell biological and physiological approaches we are currently
characterizing the transporters and investigating the mechanisms
of their regulation and physiological role in the model plant Arabidopsis as
well as in crop plants such as the legumes (pea, French bean
and soybean) and potato. The ultimate goal of my work is nutrient
traffic control, i.e. manipulating nutrient flux and distribution
within the plant body, targeted at improving plant productivity
and nutritional quality of harvestable products.
My experience
with molecular and physiological analysis techniques, functional
cloning, and transgenic approaches to engineering of selective plant
properties provides a useful interface to other plant biologists
at WSU.
Selected
Publications
Tegeder
M., Tan Q., Grennan A. and Patrick J.W. 2007. Amino acid transporter
expression and localisation studies in pea (Pisum sativum).
Functional Plant Biology, in press.
Lee
Y.H., Foster J., Chen J., Voll L.M., Weber A.P.M. and Tegeder
M. 2007. AAP1 transports uncharged amino acids into
roots of Arabidopsis. The Plant Journal 50:305-319.
Pélissier
H.C. and Tegeder M. 2007. PvUPS1 plays a role in source-sink
transport of allantoin in French bean (Phaseolus vulgaris). Functional
Plant Biology 34:282-291.
Rentsch
D., Schmidt S. and Tegeder M. 2007. Transporters for
uptake and allocation of organic nitrogen compounds in plants.
FEBS Letter 581:2281-2289.
Tegeder
M. and Weber A.P.M. 2006. Metabolite transporters in the control
of plant primary metabolism. In Control of primary metabolism
in plants (Plaxton, W. and McManus, M., eds.), Oxford: Blackwell
Publishing. Annu. Plant Rev. 22:85-120.
Lee
Y.-H. and Tegeder M. 2004. Selective expression of a novel high
affinity transport system for acidic and neutral amino acids
in the tapetum cells of Arabidopsis flowers. Plant J
40:60-74.
Pélissier
H. C., Frerich A., Desimone M., Schumacher M., and Tegeder M.
2004. PvUPS1, an allantoin transporter in nodulated roots of
French bean. Plant Physiol 134:664-675.
Koch
W., Kwart M., Laubner M. , Heineke D., Stransky H., Frommer W.B.,and
Tegeder M. 2003. Reduced amino acid content in transgenic potato
tubers due to antisense inhibition of the leaf H+/amino acid
symporter StAAP1. Plant Journal 33:211-220.
Lalonde
S., Tegeder M., Thorne-Holst M., Frommer W.B., & Patrick
J.W. 2003. Phloem loading and unloading of sugars and amino
acids. Plant Cell and Environment 26:37-56.
Okumoto
S., Schmidt R., Tegeder M., Fischer W.N., Rentsch D., Frommer
W.B.,
& Koch W. 2002. High affinity amino acid transporters specifically
expressed in xylem parenchyma and developing seeds of Arabidopsis.
J Biol Chem. 277(47):45338-46.
Tegeder,
M., Offler, C.E., Frommer, W.B., & Patrick, J.W. 2000. Amino
acid transporters are localized to transfer cells of developing
pea seeds. Plant Physiol 122:319-326.
Tegeder,
M., Thomas, M., Hetherington, L., Wang, X.-D., Offler, C.E. & Patrick,
J.W. 2000. Genotypic differences in seed growth rates of Phaseolus
vulgaris L. Factors contributing to cotyledon sink activity and
sink size. Aust J Plant Physiol 27(2):119-129.
Tegeder,
M., Wang, X.-D, Frommer, W.B, Offler, C.E, & Patrick, J.W.
1999. Sucrose transport into developing seeds of Pisum sativum
L. Plant Journal 18:151-161. |
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