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Dr.
Hanu R. Pappu
.jpg) 509-335-3752
hrp@wsu.edu
Associate Professor and President Sam Smith Distinguished Professor in Plant Virology, Department of Plant Pathology. Ph.D. 1990, University
of Alberta, Edmonton
Plant Pathology webpage
Research
Viruses offer a simple yet elegant model systems to study the molecular basis of their interactions with host plants as these interactions could result in varying degrees of disease development, in some cases, a lethal response in their hosts. Understanding the basis of these interactions would provide clues to developing strategies for managing virus infections and virus epidemics in crops.
My research activities are focused on genomics and proteomcis of DNA and RNA viruses that are pathogenic to economically important crops: molecular characterization, gene structure-function relationships (Pappu et al. PNAS 90:3641); molecular evolutionary studies using viral genes as markers for attribution (Pappu et al. Arch. Virol. 151:1015); identification and development of novel promoters from plant pararetroviruses for expression of foreign genes in plants; molecular studies on plant pararetroviruses that exist as integrants in their host plant genomes (Pahalawatta et al., Virology 376:253), and use of RNA and DNA viruses of plants as tools for studying virus-host and virus-vector interactions.
Specific research interests/exerptise include:
- Molecular and biotechnological approaches for characterization and control of viral diseases of crop plants.
- Specific areas of interest are genomics, proteomics, molecular epidemiology, conventional and transgenic resistance, virus detection and diagnosis, and host-virus interactions.
- Current focus is on tospoviruses, luteoviruses, potyviruses, and caulimoviruses
- Crops include vegetables, nursery/ landscape/ ornamentals, legumes, and cereals.
- Other areas of expertise include environmental impact assessments, and regulatory framework for transgenic plants/GM crops; impact of plant biotechnology on society; adoption trends of plant biotechnology in the US and other parts of the world
Ongoing projects include:
- Thrips and tospoviruses in various vegetable and legume cropping systems
- New and emerging viruses affecting nursery and landscape industry
- Biological and molecular studies of Dahlia mosaic caulimovirus
- Molecular basis of viral pathogenecity using potato-PVS as a model sytstem
- Ecology, epidemiology, and molecular studies on legume viruses
Selected
Publications
Pappu, H.R. 2008. Tomato spotted wilt virus (Bunyaviridae). In: Encyclopedia of Virology. 3rd edition. Brian Mahy and Marc van Regenmortel (Eds.). Elsevier Ltd, Oxford, UK. In press.
Pahalawatta, V., K.L. Druffel, and H.R. Pappu. 2008. A new and distinct species in the genus Caulimovirus exists as an endogenous plant pararetroviral sequence in its host, Dahlia variabilis. Virology 376: 253-257.
Pahalawatta, V., K.L. Druffel, S.D. Wyatt, K.C. Eastwell, and H.R. Pappu. 2008. Genome structure and organization of a novel and distinct species of genus Caulimovirus (Family Caulimoviridae) associated with dahlia mosaic. Archives of Virology 153:733-738.
Mandal, B., S. Mandal, A.S. Csinos, N. Martinez, A.K. Culbreath and H.R. Pappu. 2008. Biological and molecular analyses of the acibenzolar-S-methyl-induced systemic acquired resistance in flue-cured tobacco against Tomato spotted wilt virus. Phytopathology 98:196-204.
Miglino, R., A. Jodlowska, H.R. Pappu, and A.R. van Schadewijk, A. R. 2007. A highly sensitive and semi-automated method for genus-wide and species-specific detection of plant viruses of ornamental bulb crops. J. Virological Methods 146:155–164.
Pappu, H.R., L.J. du Toit, H.F. Schwartz and K. Mohan. 2006. Sequence diversity of the nucleoprotein gene of Iris yellow spot virus (genus Tospovirus, family Bunyaviridae) isolates from the western region of the United States. Archives of Virology 151:1015-1023.
Pappu, H.R. 2004. Insect pollinated crops. Pp 35-48, In: Proceedings of the Workshop on Confinement of Genetically Engineered Crops during Field Testing. USDA-APHIS, Biotechnology Regulatory Services, Riverdale, MD. September 13-14, 2004.
Yang, H., P. Ozias-Akins, A. K. Culbreath, D. W. Gorbet, J. R. Weeks, B. Mandal and H. R. Pappu. 2004. Field evaluation of Tomato spotted wilt virus resistance in transgenic peanut. Plant Disease 88:259-264.
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