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Dr. Dorrie Main
.jpg) 509-335-2774
dorrie@wsu.edu
Associate Scientist/Associate Professor of Bioinformatics, Department
of Horticulture and Landscape Architecture. Ph.D. 1995, Strathclyde
University, Glasgow, Scotland.
Research
My main research interests are
computational analysis and data mining of DNA sequences, development
of integrated genomic databases and analysis tools, and comparative
genomics of plants with particular emphasis on the economically
and nutritionally important Rosaceae family (apple, peach, cherry,
strawberry, rose, apple). Active projects are as follows: (1) development
of a web accessible Genome Database for Rosaceae, (2) synteny analysis
of resistance genes in apple, peach, strawberry, apricot and plum,
(3) annotation of the peach genome, (4) identification of functional
domains in Arabidopsis and rice, (5) development of microarray
resources for analysis of repeat region functionality in Arabidopsis,
(6) development of a www accessible Cotton Microsatellite Database
(CMD), (7) development of protocols and computational pipelines
for processing, analysis and visualization of genomic and cDNA
sequences, (8) development of algorithms to identify unigenes from
gene fragments; and development of www accessible sequence processing
resources for smaller scale genomic laboratories and researchers.
Selected
Publications
S. Jung, D. Main, M. Staton, I. Cho, T. Zhebentyayeva, P. Arus,
A. Abbott. 2006. Synteny conservation between the prunus genome
and both the present and ancestral Arabidopis genomes. BMC Genomics
7(1):8.
Anna Blenda, Jodi Scheffler, Brian Scheffler, Jean-Marc Lacape,
John Z. Yu, Sook Jung, Meg Staton, Michael Palmer, Christopher
Jesudurai, Sriram Muthukumar, Preetham Yellambalase, Stephen Ficklin,
Robert Eschelman, Mauricio Ulloa, Sukumar Saha, Ben Burr, Shaolin
Liu, Tianzhen Zhang, Deqiu Fang, Alan Pepper, Siva Kumpatla, John
Jacobs, Jeff Tomkins, Roy Cantrell and Dorrie Main. 2006. CMD:
A Cotton Microsatellite Database Resource for Gossypium Genomics.
BMC Genomics 7:132.
Frelichowski JE, Palmer M, Main D, Tomkins JP, Ulloa M. 2006.
New cotton BAC-derived microsatellites and genetic mapping. Molecular
Genetics and Genomics 275(5): 479-491.
Kevin M Folta , Margaret Staton, Philip J Stewart, Sook Jung ,
Dawn H Bies, Christopher Jesdurai and Dorrie Main. 2005. Expressed
sequence tags (ESTs) and simple sequence repeat (SSR) markers from
octoploid strawberry (Fragaria × ananassa). BMC Plant Biology
5:12.
Horn R, Lecouls AC, Callahan A, Dandekar A, Garay L, McCord P,
Howad W, Chan H, Verde I, Main D, Jung S, Georgi L, Forrest S,
Mook J, Zhebentyayeva T, Yu Y, Kim HR, Jesudurai C, Sosinski B,
Arus P, Baird V, Parfitt D, Reighard G, Scorza R, Tomkins J, Wing
R, Abbott AG. 2005. Candidate gene database and transcript map
for peach, a model species for fruit trees. Theor Appl Genet. 110(8):1419-28.
Sook Jung, Albert Abbott, Christopher Jesudurai, Jeff Tomkins
and Dorrie Main. 2005. Frequency, Type, Localization and Annotation
of SSRs in Rosaceae ESTs. Funct. Integr. Genomics 5:136-43.
Sook Jung, Christopher Jesudurai, Margaret Staton, Ilhyung Cho,
Albert Abbott, Jeffrey Tomkins, Dorrie Main. 2004. GDR (Genome
Database for Rosaceae): integrated web resources for Rosaceae genomics
and genetics research. BMC Bioinformatics 5(1):130.
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