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Dr.
Kulvinder S. Gill
.jpg) 509-335-4666
ksgill@wsu.edu
Vogel
Endowed Chair in Wheat Breeding and Genetics, Ph.D. (Genetics)
1990, Kansas State.
Research
Wheat
is the world’s most important food crop and WSU has perhaps
the largest group in the nation working on understanding and manipulating
the wheat genome. Goal of my program is to understand mechanism
of agronomically important genes and manipulate these genes for
crop improvement using genomics and informatics tools. While studying
distribution of genes on cereal chromosomes, we have learned that
most wheat genes are present in gene-rich regions, which encompass
only about 10% of the genome. These gene-rich regions are interspersed
by large blocks of repeated DNA sequences. Although recombination
only occurs in the gene-rich regions, recombination among various
gene-rich regions may vary as much as 20 fold. Currently we are
trying to understand structural and functional organization of
the gene-rich regions and the recombination hot spots. Secondly,
chromosome pairing and homology search is a poorly understood process
but it is important not only for basic understanding of biology
but also for alien introgression in crops such as wheat where genes
from wild relatives are routinely transferred into cultivated wheat.
Manipulation of chromosome pairing control can make this process
efficient and directed. Ph1 gene of wheat is the principal regulator
of chromosome pairing and we are working on understanding its mode
of action.
Selected
Publications
Chao,
S., G.R. Lazo, G.R., F. You, C.C. Crossman, R.E. Miller, D.D.
Hummel, N. Lui1, D. Laudencia-Chingcuanco1, E. Butler, J.A. Anderson,
T.J. Close, J. Dubcovsky, J. Dvorák, B.S. Gill,
K.S. Gill, J.P. Gustafson, S.F. Kianian, N.L.V. Lapitan, H.T. Nguyen,
M.E. Sorrells, P.E. McGuire, C.O. Qualset, and O.D. Anderson.
2005. Use of a Large-Scale Triticeae EST Resource to Reveal Gene
Expression Profiles in Hexaploid Wheat (Triticum aestivum L.). Genome
(under review).
Muharrem Dilbirligi, Mustafa Erayman, B. Todd Campbell, Harpinder
S. Randhawa, P. Stephen Baenziger, Ismail Dweikat, Kulvinder S.
Gill. 2005. High-Density Mapping and Comparative Analysis of Agronomically
Important Traits on Wheat Chromosome 3A. Genomics (accepted).
Muharrem Dilbirligi, Mustafa Erayman and Kulvinder S. Gill. 2005.
Analysis of Recombination and Gene Distribution in 2L1.0 Region
of Wheat (Triticum aestivum L.) and Barley (Hordeum
vulgare L.). Genomics (in press).
Mahmood, D., P.S. Baenziger, H. Budak, K.S. Gill, and I. Dweikat.
2004. The Use of Microsattelite Markers for Detection of Genetic
Similarity Among Winter Bread Wheat Lines for Chromosome 3A. Theor
App Genet 109:1494-1503.
Li, Lijia, K. Arumuganathan, K.S. Gill, and Yunchun Song. 2004.
Flow Sorting and Microcloning of Maize Chromosome 1. Hereditas 141:55-60.
Lazo GR, 20 co-authors, K.S. Gill, 14 co-authors. 2004. Development
of an Expressed Sequence Tag (EST) Resource for Wheat (Triticum
aestivum L.): EST Generation, Unigene Analysis, Probe Selection
and Bioinformatics for a 16,000-Locus Bin-Delineated Map. Genetics
168:585-593.
Zhang, D., 37 co-authors, K.S. Gill, 6 co-authors. 2004. Construction
and Evaluation of cDNA Libraries for Large Scale EST Sequencing
in Wheat (Triticum aestivum L.) Genetics 168:595-608.
Ramalingam J., 22 co-authors, K.S. Gill, 14 co-authors. 2004. Structure
and Functional Analysis of Wheat Chromosomes Based on Expressed
Sequence Tags (ESTs) Related to Abiotic Stresses. Genetics (Accepted).
Qi, L. 22 co-authors, K.S. Gill, 21 co-authors. 2004. A Chromosome
Bin Map of 16,000 EST Loci and Distribution of Genes Among the Three
Genomes of Polyploid Wheat. Genetics 168:701-712.
Hossain, K.G., 22 co-authors, K.S. Gill, 15 co-authors. 2004. A
2148 EST Loci Map of Group 7 Chromosomes of Wheat (Triticum
aestivum L.). Genetics 168:687-699.
Randhawa, H.S., 30 co-authors, K.S. Gill. 2004. Deletion mapping
of homoeologous group 6-specific wheat ESTs. Genetics 168:677-686.
Linkiewicz, A.M., 22 co-authors, K.S. Gill, 7 co-authors. 2004.
A 2500-Loci Map of Wheat Homoeologous Group 5 Provides New Insights
on Gene Distribution and Colinearity with Rice. Genetics 168:665-676.
Mitahudin, 25 co-authors, K.S. Gill, 22 co-authors. 2004. Analysis
of Wheat EST Loci on Wheat Chromosome Group 4. Genetics 168:651-663.
Munkvold, J.D., 8 co-authors, K.S. Gill, 17 co-authors. 2004.
Analysis of the Wheat Chromosome Group 3 Deletion Maps. Genetics
168:639-650.
Conley, E.J., 28 co-authors, K.S. Gill, 5 co-authors. 2004. A 2600-Loci
Map of Wheat Homeologous Group 2 Reveals Two Interstitial Gene-Rich
Islands and Provides Insight into Genome Structure and Colinearity
with Rice. Genetics 168:625-637.
Peng J.H., 8 co-authors,
K.S. Gill, 17 co-authors. 2004. A Physical Map of Expressed Sequence
Tags and Functional Genomics in the Group 1 Chromosomes of Wheat,
Triticum aestivum. Genetics 168:609-623.
Erayman, Mustafa, D. Sandhu, D. Sidhu, M. Dilbirligi, S. Baenziger,
and Kulvinder S. Gill. 2004. Demarcating the Gene-Rich Regions of
the Wheat Genome. Nucleic Acid Research 32 (12): 3546-3565.
Mater, Y.M., P.S. Baenziger, I.M. Dweikat, K.S. Gill, R.A. Graybosch,
L.C. Whitcher, C.A. Baker, J.E. Specht and Ismail Dwiekat. 2004.
Linkage Mapping of Powdery Mildew and Greenhub Resistance Genes
on Recombinant 1RS from 'Amigo' and 'Kavkaz' Wheat-Rye Translocations
of Chromosome 1RS.1AL. Genome 47:292-298.
Campbell, B.T., P.S. Baenziger, K.M. Eskridge, H. Budak, N.A. Streck,
A. Weiss, K.S. Gill, and M. Erayman. 2004. Using Environmental Covariates
to Explain Genotype x Environment and QTL x Environment Interactions
for Agronomic Traits on Chromosome 3A of Wheat. Crop Sci. 44:620-627.
Dilbirligi, M., M. Erayman, D. Sidhu, D. Sandhu, and K.S. Gill.
2004. Identification of Wheat Chromosomal Regions Containing Expressed
Resistance Genes. Genetics 166:461-481.
Dilbirligi Muharrem
and Kulvinder S. Gill. 2004. Identification and Analysis of Expressed
Resistance Gene Sequences in Wheat. Plant Mol. Biol. 53:771-787.
Sidhu, Deepak and Kulvinder S. Gill. 2004. Distribution Of Genes
And Recombination In Wheat And Other Eukaryotes. Plant Cell Tissue
and Organ Culture 79:257–270.
Tuna, M., K.P. Vogel, Kulvinder S. Gill, and K. Arumuganathan.
2004. Cytogenetic Characterization of Smooth Bromegrass Genomes.
Crop Science 44:31-37.
Kumlay, A.M, P.S. Baenziger, K.S. Gill, D.R. Shelton, R.A. Graybosch,
A.J. Lukaszewski, and D.M. Wesenberg. 2003. Understanding the Effect
of Rye Chromatin in Bread Wheat. Crop Sci. 43:1643-1651.
Sorrells, Mark E, 33 co-authors, Kulvinder S. Gill, C. Steber,
M.K. Walker-Simmons, P.E. McGuire, and C.O. Qualset. 2003. Comparative
DNA Sequence Analysis of Wheat and Rice Genomes. Genome Res. 13(8):1818-1827.
Akhunov, Eduard D., 26 co-authors, Kulvinder S. Gill, Walker-Simmons,
M.K., Steber, C., Patrick E. McGuire, Calvin O. Qualset, and Jan
Dvorak. 2003. The Organization and Rate of Evolution of Wheat Genomes
are Coorelated with Recombination Rates Along Chromosome Arms. Genome
Res. 13(5):753-763.
Akhunov, E.D., 26 co-authors, Kulvinder S. Gill, Patrick E. McGuire,
Calvin O. Qualset, and Jan Dvorak. 2003. Synteny Perturbations Between
Wheat Homeologous Chromosomes by Gene Insertions and Deletions in
Regions of High- and Low-Recombination. Proc Natl Acad Sci USA.
100(19):10836-10841.
Campbell, B.T., P.S. Baenziger, K.S. Gill, K.M. Eskridge, H. Budak,
M. Erayman, I. Dweikat, and Y. Yen. 2003. Identification of QTLs
and Environmental Interactions Associated with Agronomic Traits
on Chromosome 3A of Wheat. Crop Sci 43:1493-1505.
Sandhu, D. and Gill, K.S. 2002. Gene-Containing Regions of Wheat
and the Other Grass Genomes. Plant Physiology 128(3):803-811.
Sandhu,
D. and Gill, K.S. 2002. Structural and Functional Organization
of ‘1S0.8 Gene-Rich Region’ in Triticeae. Plant Molecular
Biology 48(5):791-804.
Sandhu, D., Champoux, J., Bondareva, S. and Gill, K.S. 2001. Identification
and Physical Localization of Useful Genes and Markers to a Major
Gene-Rich Region on Wheat Group 1S Chromosomes. Genetics 157:1735-1747.
Gill, K.S., Arumuganathan, K. and Lee, J.-H. 1999. Isolating Individual
Wheat (Triticum aestivum) Chromosome Arms by Flow Cytometric
Analysis of Ditelosomic Lines. Theor. Appel. Genet. 98(8):1248-1252.
Gill, K.S., Gill, B.S., Endo, T.R. and Boyko, E. 1996. Identification
and High-Density Mapping of Gene-Rich Regions in Chromosome Group
5 of Wheat. Genetics 143:1001-1012.
Gill, K.S., Gill, B.S., Endo, T.R. and Taylor,
T. 1996. Identification and High-Density Mapping of Gene-Rich
Regions in Chromosome Group 1 of Wheat. Genetics 144:1883-1891.
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